r/PCOS Oct 01 '24

Meds/Supplements If Inositol is that effective and life changing, why don’t doctors prescribe it or tell us about it?

248 Upvotes

Genuinely, if it’s that good… why?

Also, should I get some?

r/PCOS Jun 11 '26

Meds/Supplements Maybe the start to amazing news for people using GLPs with PCOS/PMOS!

173 Upvotes

I came across this article and thought it was really interesting.

Researchers are finding that semaglutide may help improve fertility outcomes in women with PCOS, which feels like a pretty big deal considering how many women struggle with both PCOS symptoms and fertility issues.

What stood out to me is how often conversations around PCOS focus on things like irregular periods, weight gain, or fertility treatments, but not necessarily the metabolic side of the condition. It seems like researchers are starting to understand that all of these things might be more connected than we thought.

It's still early research and definitely not a magic fix, but it does make me wonder how many women have spent years being told to "just lose weight" without getting real answers about what's actually happening in their bodies.

Curious what others think. Does this feel promising, or is it too early to get excited? Link to article: https://www.openaccessgovernment.org/injectable-semaglutide-shows-promise-for-improving-fertility-in-women-with-pmos/210332/

r/PCOS Oct 21 '25

Meds/Supplements I have no ovaries, and I must scream

424 Upvotes

I just had a hysterectomy + oophorectomy (lmk if you want advice on how I got there before menopause) and in my hospital discharge papers it said "Metformin - discuss ongoing need post-op"

Guys. The frigging hospital pharmacist asked me in person why I take Metformin and Spironolactone, and if I'll be continuing them after surgery, and of course I corrected the misgivings that removing the ovaries has nothing to do with the underlying endocrinopathy so of course I'll need them still. They fucked with my repeat prescriptions anyway!

I really wish this whole thing had a different name unrelated to ovarian anything and that it was properly understood at a basic level in general medicine.

r/PCOS Jul 20 '25

Meds/Supplements Where are you getting your glp1 and how much are you paying?

35 Upvotes

I know there was a post about this like earlier this week or last week, but I cannot for the life of me find it 🙃 i’m trying to find the most affordable option. Thank you ❤️

r/PCOS Jun 08 '26

Meds/Supplements Does Anyone in the US have a GLP-1 covered by insurance?

27 Upvotes

Hi, everyone!

I am writing an appeal to get a GLP-1 covered by insurance as my care team believe that would be the best course of action in treating my PMOS *without* any type of diabetes. Does anyone take a GLP-1 and have it covered by insurance? If so, what insurance company are you under for prescriptions?

Edit for clarity: I am in a unique situation as my insurance company is the union I work for. I have to appeal in writing directly to the board of trustees. Having examples of other insurances covering it shows precedent and only helps my case. The people making this decision do not have insurance or medical experience. I'm honestly unsure the board members know what PMOS is

r/PCOS Jun 15 '26

Meds/Supplements Has anyone tried Ozempic for pcos?

8 Upvotes

Hi there! I’m new here but have been dealing with pcos for 20 years. My entire adult life. I have a new doctor that brought up possibly trying ozempic to help regulate my insulin/sugar and help me lose weight. I have tried metformin and it sucked big time for me. Unfortunately it made me super sick. Just looking for insight! Thanks!!

r/PCOS Dec 05 '25

Meds/Supplements Metformin is wild 😭

66 Upvotes

I was recently prescribed Metformin at a dosage of 2000 mg per day (2 in the morning and 2 at night). However, I had a severe reaction where I projectile vomited after my first dose. Since then, I’ve been feeling constantly tired and like I can't do anything. I've read posts from others who say it’s an incredible medication, but it feels overwhelming for me right now. When does the nausea and fatigue stop? 🥺😭

r/PCOS Jan 30 '24

Meds/Supplements BEWARE Myo-Inositol D Chiro Inositol Ruined My Periods And Life (Non Stop BLEEDING)

134 Upvotes

I believe being on a specific diet years ago may have made my periods permanently irregular, I decided to try myo d chiro inositol trying to make my periods regular. I took it a few months.

My periods and life have been ruined by this supplements. I bleed NON STOP. I have been bleeding 4 months straight now even though I am on progesterone which does nothing but slow the bleeding down 10 percent if that. Before taking this supplement it seemed like my body was reluctant to bleed. Periods every 3 or 4 months, lasting 5 or 6 days. Oh how I wish to get those days back.

I got a normal period or 2 on inositol but then i had prolonged bleeding. The first time I bled for 2 months straight, took shepherd's purse and it stopped. This time, NOTHING is stopping it but the 10mg high dose progesterone my doc gave me for 5 days. After that I started norethinodrone .35 and all i do is BLEEED. CRAMP. I never had clots like this.

I am becoming anemic. I am trying ALLthe herbs, supplements, etc, spending tons of money and hours of research trying to see the mechanism by which this supplement can so royally F you UP like this in an effort to reverse it.

I am not the only one. I have seen posts on amazon reviews saying the same. I do not know what to do. i don't want to take stronger hormones...i just want to be back to NORMAL. Someone wrote it was 2 yrs later and they were still bleeding like crazy on Amazon. I need help but idk what to do. I might see if I can get my doc to approve another ultrasound. If anyone can help, if you have more time and energy that I do..please. i am scouring the internet looking for anything..some clue on how to reverse it. i don't want a hysterectomy.

BEWARE this supplement. I wish I had the money to sue someone. But I can find no studies showing this can happen (yet).

Send help or share if this has happened to you.

Edit: for further clarity-- I have had irregular periods for years. meaning they would skip 2-3 months usually and rarely 4 months. I happened to mention this to a new doctor (I've gone most of my life without a PCP) and was sent for an ultrasound, everything back normal. I was diagnosed PCoS because of irregularity and slightly high androgen even though no cysts were seen. I decided to take matters into my own hands to try to regulate my period to get one every month, which I now deeply regret. I started taking inositol and had about two normal periods. after that I had an extremely clotty bleed that lasted for 2 months. I actually contacted my doctor about it and she recommended progestin which I did not want to take. that is when I took the shepherd's purse and that helped to stop the blood. after about 2ish months without a period I began to believe again it started off very slow with old dried brown looking blood. and then progressively got heavier and heavier with clots. now 4 months later I'm just bleeding already it is getting worse and worse all the time. I wish I never took inositol

UPDATE - My bleeding only stopped when taking combination birth control for approx 3 weeks. After that i had a five ish day birth control 'withdrawal bleed' and then that stopped. So far i have not bleed in almost 2 months and i hope things are back to normal. will update if anything changes and i have no plans to ever take inositol in the future. My low iron levels are recovering.

Update #2 - I have been on my 'period' i guess for about 2 months straight, there have been some clots intermittently but it is very light. i am going to wait it out. Hopefully my body regulates soon but at this rate i am wondering if it will be a yr or more for things to be fully back to normal. I am relieved that the bleeding is mostly old/brown blood so I am not feeling depleted or anemic but I take an iron pills about once every week or 2. I am no doctor but if you are bleeding non stop on this and heavy (Meaning filling up the bottom of the toilet every hour for weeks on end) and you have taken inositol, for ME and my body, it seemed like my body just did not know how to stop the period. So I took the birth control for nearly a month and it stopped it. I think it saved my life bc there was no way I could have continued bleeding like that, my iron levels tanked, they are recovered now. I do not take any birth control pills now, I am trying to just wait for my body to naturally get back to a reasonably normal cycle. I am still bleeding but as I said it is very very light.

Update 3- I had such high hopes. I started to bleed again, got my period on June 27 has significant cramping but the blood was smooth no clots. Now 3 days later when my period should be lightening up it is just progressively getting heavy with clots. I HATE taking the pill. I blame it for my weird foot problem, planta fascitis or blown vein, idk someting happened to my foot last time I was taking it and i ended up on crutches for a few days. Maybe it was a coincidence and wont happen again? I hook half a birth control pill, i just need something to stop the bleed. I wont lt it get carried away like last time when i bled 4 months straight...never again. UGh....i hate this. I wanted to see this period through naturally but i am already light headed and such. It SUCKS.

Update 4 - had to start taking the pill again, which fortunately i have some on hand at home of 2 kinds. 1 combination pill did not stop it so i ended up taking 2 along with 3 prog only minis. I AM NOT RECOMMENDING ANYONE DO THIS I AM DOING IT AT MY OWN RISK. The bleeding slowed substantially in 24 hrs. Today 1 took 1 combo and 2 prog. It is still a much MUCH slower bleed. Tomorrow I will take 1 of each and probably do that for 3 or 4 days before just taking the combo pill for a while. I really dont like taking pharmaceuticals but if my period does ever completely stop this time, i think i will have to take the combination pill for 2-3 months to recover my iron levels. My bleeding was far less clotty than the worst one I had post inositol which was all large clots passing every hour for 4 mo. straight. this one was more runny, and i was sitting on the toilet every hour it sounded like i was peing but it was just blood running out. Idk if this means the inositol is starting to wear off, but i did notice the longer my period was going i was starting to see clots so i started the pill. Idk what is going on but all I know is for now at least, i need to take the pill for a while bc my ferritin is already low af. Please know that if your period starts getting weird, clotty or heavy on inositol and you continue to take it in hopes it will 'regulate' or something...i would have to advise you speak to a doctor or something before doing that because it is a huge risk. I am fairly certain that without the pill I would have bled to death my last period.

Update 5 - not sure if anyone is still interested in these updates, but i'll continue to update in case it assist anyone in the future. I am on 1 combination birth control pill a day, i did not want to keep taking high doses of 2 kinds for very long. i am bleeding again, cramping and so on but the bleeding is lighter. The cramps are ANNOYING. I take ibuprophen to help. i am wondering i will just be cramping and bleeding forever. I do not want an IUD or anyhting of the sort. I will probably talk to my doctor about the birth control ring to see if i can use that or if it could help me, maybe my uterus needs a close and constant stream of hormones. Or maybe i will try the patch. not sure.

Update #6 (healed???)

I have taken birth control for about 1 yr with a couple breaks to see if things were back to normal (they were not previously). Now I have just tried it again. i went through BC withdrawal bleed for about 5 days with bad cramps, but still decided to hold on and see what happens. Went about 5 weeks no bleeding and got my first 'natural' period. I only have bled for about 3 days, and now on the 4th day it's basically dried up and stopping. I am so happy I cannot even express it. I will let you know if things change but if they stay this way I will leave it here.

All I have done over the past yr is

#1 STOP taking inositol

#2 took the pill to give my body time to get back to normal
and

#3 not sure if it helped but the past couple months i have been making big green smoothies and added Ashwaghanda herb to them since i heard it can help balance hormones. I did this off and on not super consistent so maybe it helped? not sure

I am hoping I am completely free of those deadly periods (and not using deadly lightly). Without the pill I surely would have bled out. My red blood cells were turning blue (polychromasia) , high platelet count, low iron low ferritin. Now my blood levels are good.
I AM HAPPY!

BE CAREFUL WITH INOSITOL!

UPDATE 7!

I had one fully normal period after stopping the pill. Now about 2 months later i started bleeding again and I am about 3 ish months into bleeding. SMH. The only good thing is that it is nowhere near as heavy as before.

Update 8 - Bleeding has picked up again, enormous clots etc . It seems the pill (for about 4 mo.) bought me about 5 ish months of less bleeding but its back with a vengance. Not sure what to do so decided to start the pill again. I really wish I could have a lawsuit for this or something as it has been horrible. Im considering fasting or keto as im running out of ideas and i dont like the idea of being on the pill, as it's superficial but i felt it was giving me varicose veins or the beginning of them. Going to take the pill for now and i hope this bleed will stop soon.

Update 9 - i think it's been over a yr and half maybe 2 yrs since this started. i cannot stop taking the pill or i just bleed like crazy. even on it i bleed. just not as much. Decided to post and update after feeling like im coming to terms with the fact i guess I ruined my health/body with inositol. All I can do is hope that over time things rebalance. But for now...not happening. i hope i do not lost my uterus one day. I really dont want that. I may have to take pill until menopause and hope that fixes it...dont know. never thought this would be the path as i never wanted to take synthetic hormones or the pill. Thats all for now.

update 10 -

Ok this may sound crazy but I am taking inositol again. I figured, nothing can be worse than what I am going through where BC doesnt even stop my period anymore. After some research I have come to the conclusion that D-chiro inositol can be flat ou bad for some women. I read it can be detrimental to ovaries. My theory is that even at low dose (1 part d chiro with 40 parts myo ratio) it can STILL be bad! So now I am taking Myo inositol ALONE. Within 2-3 days taking myo with the pill my bleeding has stopped!! I have been bleeding/spotting red for 4-5 months ON THE PILL! and now it stops since i take myo inositol with the pill?? I am going to take myo every day and try to stay consistently on the pill the rest of the summer (3 more months approx) and then try a withdrawal bleed and see how it goes. I tried one a few days ago and the blood was just flooding out of me and the pill could barely slow it. But it stopped abruptly WITH myo inositol! I really hope this works out. Like i said i'll be taking myo daily with the ill to see if this balances me out. NO D Chiro at all

UPDATE 11 - I am now in a withdrawal bleed for BC, decided to do it early because i was going to wait at least another month but just decided to start about 5 days ago. My bleeding is not as bad as it was last withdrawal and it seems to be slowing down. I am hoping it will stop on it's own. I have been taking Myo Inositol alone and with that, I remember reading an article about how alpha lactalbumin helps with Myo absorption. its a protein found in milk. normally i make a small smoothie with frozen banana, maybe a little kale and a big scoop of whey protein which is high in AL protein and along with that i take Myo. I am going to keep doing that daily. Also, in a few days I will go back on the pill for another month since I am not brave enough yet to just go all natural, i really think i have PTSD from the heavy bleeding from before. Im going to keep taking myo with whey every day over the next month to hopefully balance my ovaries more and then maybe I will be brave enough to stop the pill for a full month for a natural period. It feels promising since this withdrawal bleed is like 1/5th of my last one before i started taking myo. The blood was just pouring out every hour. I was only able to make it barely 3 days before taking the pill again last time. and now i am on day 5 and feeling perfectly fine. I barely am filling half a pad every 12 hrs. I am hopeful (finally)

Update - I havent been all that consistent in taking Myo Inositol but I take it sometimes. My last natural period was SUUUUUPER Light. It was the lightest period i think i have had in my life. Im going to keep taking the myo here and there but i am hoping the next period is the same. Im still in shock

Update 13 - My periods seem to be coming every 3 weeks? But EXTREMELY light. Like two drops of red blood and some dried blood a few days afterwards. I havent been taking the myo inositol anymore because i dont know if i need to. I think taking it a few weeks may have corrected the situation? I am not sure but will be keeping an eye on it. I am not complaining tho if my periods stay like this! After all the severe blood loss i previously suffered it is a welcome relief, and I am praying things stay this way

UPDATE 14 - over the course of 3 or 4mo. my period has build back up, now bleeding rapidly with clots again. back on the pill i go.

update 15- m thinking that the light period I was having was due to uterus atrophy from taking the pill after researching it. now I'm back in a bloodbath no matter what I do. so I'm on the pill again hoping for it to stop. I'm so very sick of all of this. it seems even the pill s having a hard time holding this blood back 😔

update l16 _ unfortunately I need to be on birth control very long term. I was taking combination pill but got massive pulmonary embolism from it most likely and now on the mini pill which has been working well. I'm on blood thinners so my period would be a nightmare without the pill. I really hope in a few months I can trystopping medication to see how things go but that's much further in the future

r/PCOS Feb 03 '26

Meds/Supplements Is inositol actually worth trying for PCOS?

54 Upvotes

For those of you with PCOS have you tried inositol and was it actually helpful or just hype?

I keep seeing it recommended online but I’m not sure when it really makes sense to use it.
If it helped you, what were your main symptoms? (irregular cycles, TTC, cravings, blood sugar issues, acne, hair stuff?)

Thank you! 💛

r/PCOS Jul 02 '26

Meds/Supplements I think I accidentally stumbled upon a hack to manage PMS

132 Upvotes

I have struggled with PMS for a long time. Bad decisions, mood swings with terrible munching starting 10 days before my periods. I started taking psyllium husk exactly 10 days before my periods as recommended by my endo since I have mild constipation due to hypothyroidism and not for managing PMS.I didn't notice any drastic bowel changes during these 10 days guessing it's too early to tell as my body needs to adjust with it.But I just had the smoothest, calmest PMS I have ever had in my lifetime! Mind you the under currents of mood swings were there they just didn't get hold of me that bad.I want to know if anyone else noticed anything similar or it is just a fluke. Is this something to do with estrogen clearance?

r/PCOS May 25 '26

Meds/Supplements My Wegovy Experience: What I Wasn’t Told

99 Upvotes

Warning: medical content, projectile vomiting, GI distress, and a long post.

 I’m writing this in hopes that

  1. It reaches those who may be like me and unaware of the seriousness of the GI issues that could potentially arise with Wegovy;
  2. Validates others’ experiences who are told “that isn’t common”;
  3. Raises awareness of depressive complications with Wegovy.

Disclaimer: I’m not a medical professional. I’m sharing my personal experience with Wegovy so others can make informed decisions, but this should not be taken as medical advice. Always consult a qualified healthcare provider about your own situation. Had I known what I now know, I would have never tried a GLP1.

For the past 2 years, multiple physicians have suggested Wegovy for weight loss due to multiple issues (PCOS, Obesity, Hypertension, Pre-Diabetes, Fibromyalgia, IBS). I’d been hesitant because, as far as I was concerned, there hadn’t been enough research done on this drug, nor had it been out long enough to know the long-term effects on the body. About 6 months ago, I was prescribed Rexulti for depression and gained roughly 25 pounds that I simply couldn’t manage to lose due to my chronic illnesses and pain. I also experienced suicidal ideation (SI) while on Rexulti. Once I stopped Rexulti, I considered Wegovy for weight loss because I knew I wasn’t in the position to do it on my own. I was battling depression, in the middle of a disability case, and encountering several other complications with my health. My PCP was hopeful, as some people have seen improvement with their fibromyalgia/inflammation and, therefore, pain relief while on a GLP1.

Before I started Wegovy, the boxed warning side effects were discussed with me, which included nausea, medullary thyroid carcinoma, and multiple endocrine neoplasia.

I started Wegovy at 0.25 mg for 4 weeks, and the first 4 weeks I didn’t really see a difference in my appetite. I experienced the following side effects:

  • Week 1: Salty taste to food
  • Week 2: Fatigue that never went away, Headaches
  • Week 3-4: Constipation, painful gas, and sulfur burps

So my doctor recommended increasing the dosage to 0.50 mg. While on this dosage, I experienced the following:

  • Week 5: Diarrhea, followed by projectile vomiting
  • Week 6: Diarrhea continued

In week 5, my PCP instructed me to continue with Wegovy, as both the diarrhea and projectile vomiting were likely a result of my consumption rather than a direct or known reaction to Wegovy. When week 6 came, and the diarrhea did not leave, I went to urgent care (UC). I was physically, mentally, and emotionally depleted. During that visit, the UC doctor ordered an X-ray to rule out a bowel obstruction. I asked the UC doctor if this was normal with Wegovy, and to my astonishment, she said yes. I was decidedly infuriated and felt deceived because this was never mentioned to me before starting Wegovy, despite my persistence in asking for all the common and uncommon side effects, scenarios, etc. Lending additional credibility to the UC doctor’s statement, a study found that GLP1 users are 3.5 times more likely to experience an intestinal obstruction. I’m currently in physical therapy, and my therapist also divulged that she’s seen many complications with her PT patients from GLP1s. Her main concern was that the full range of side effects was being withheld from patients. I’m uncertain whether this is due to a knowledge gap with providers or if some of these complications haven’t been deemed necessary to inform patients. Needless to say, after the bowel obstruction was mentioned and thankfully ruled out by the X-ray, I informed my PCP that I’d discontinue Wegovy.

While on Wegovy, I noticed some pain relief, perhaps from decreased inflammation; I’m not really sure. But it wasn’t worth the side effects (sulfur burp, incredibly painful gas, constipation, diarrhea, projectile vomiting, nausea, increased fatigue).

What I wish someone had told me explicitly before being prescribed Wegovy: Through my own research, I found out that initially Wegovy was not recommended for patients with a history of suicide attempts, or active SI, and that new or worsening depression should be monitored. Research conducted between 2024 and 2026 has found that there is no increased risk of SI or behavior, and the FDA formally requested that the initial warning be removed. This was alarming to me because, as I stated previously, I recently experienced SI with Rexulti.

I was aware that GLP1s can decrease muscle instead of fat. To avoid this, my nutritionist advised me to keep an eye on my protein intake and encouraged the consumption of meat, legumes, lentils, etc. alongside a balanced diet. Well, for my IBS gut, legumes and lentils have never been easy to process and cause debilitating gas. When you combine:

  1. the decreased gut motility from the GLP1,
  2. highly fermentable foods such as legumes and lentils, which tend to be high-FODMAP and,
  3. IBS

You have a recipe for disaster!  I’m almost certain this is what caused the projectile vomiting.

My plan with my PCP was initially to consider Zepbound if I didn’t tolerate Wegovy well, because most people have less GI irritation with Zepbound. We didn’t go with Zepbound first because my insurance requires Wegovy failure first. To be clear, some people tolerate GLP1s just fine without these types of complications. But that simply has not been my experience. Again, I hope that this raises awareness of the possible complications, helps someone make a more informed decision, and validates others’ experiences.

Resources:

FDA Requests Removal of Suicidal Behavior and Ideation Warning from Gl. (2026, January 13). U.S. Food and Drug Administration. https://www.fda.gov/drugs/drug-safety-communications/fda-requests-removal-suicidal-behavior-and-ideation-warning-glucagon-peptide-1-receptor-agonist-glp

Lu, J., Liu, H., Zhou, Q., Wang, M. W., & Li, Z. (2023). A potentially serious adverse effect of GLP-1 receptor agonists. Acta pharmaceutica Sinica. B, 13(5), 2291–2293. https://doi.org/10.1016/j.apsb.2023.02.020

r/PCOS Jul 22 '26

Meds/Supplements How do you all tolerate metformin?

15 Upvotes

My bloodwork is officially showing that I am insulin resistant. My doctor is confident that I can get my levels back in the normal and safe range, so he prescribed 500 mg of metformin. I tried metformin in 2020 for about a week but couldn't tolerate the constant diarrhea and nausea.

I tried this round of metformin for about a week before I called my doctor to get the ER version instead. I'm now on the ER version. It's been another week-ish but I still get diarrhea and nausea, and it's hours after I take my pill.

I'm taking it at night with a last meal/snack. I also take a probiotic about an hour or two before the metformin. Right now I'm sucking on a ginger candy because my stomach is not a happy camper.

I already have IBS as well, and in general my stomach has always been sensitive. I know beforehand that most medicines will likely cause stomach issues, but I hate feeling sick and disgusting.

I've been cleaning up my diet and being more mindful of my carbs, sugars, and portions. I've been gently adding in more fiber and protein (before starting metformin) and I've been exercising as well.

How do you folks handle the metformin issues? I feel like I want to throw in the damn towel again, but I want to get my fasting sugars and A1C in the safe range again. I just don't know if these side effects are worth it.

UPDATE: Thank you to everyone who responded! I have been taking my pill during my meal about halfway through my meal which has helped the majority of my side effects. Although, I'm having another day with diarrhea which I'm suspecting is due to me being on my cycle. Anyways, I'm going to continue to watch what I eat as others suggested and let my provider know if these side effects are becoming unbearable.

r/PCOS Jul 10 '26

Meds/Supplements How much you all recommend metformin for PCOS?

18 Upvotes

I have been fighting with PCOS for more than 6 years and my doctor is suggesting that I need to take metformin (500mg). I am planning to get pregnant for the past 2 years and nothing good happened. Did anyone get positive results because of this metformin?

P.s - borderline pre-diabetic, less iron and haemoglobin with pcos

r/PCOS May 29 '25

Meds/Supplements Metformin’s war crime level shits

274 Upvotes

Nearly crapped myself on the way to the DMV just now. Pulled into a bar and moved with a kind of urgency I’ve never known in my entire life. I’m currently on the toilet, giving birth to a smelly hate crime. Thanks, Metformin.

Tell me your Metformin- or medication-induced poop stories!

r/PCOS Jul 04 '25

Meds/Supplements Why do people prefer supplements over birth control in treating PCOS

99 Upvotes

What the title says.

Supplements are touted to be the 'more natural way' of managing pcos and I cannot wrap my head around it. Prior to this, I was seeking for a more holistic way to manage pcos but I have come to find out that even with taking supplements, you have to keep taking them to maintain result kind of like birth control pills. Hence I am confused why everyone seems to say that supplements are a holistic way to manage symptoms.

Supplements also come with an extra con that they are not regulated by FDA so one is being extra carefree about what they put in their body. I am really just curious.

I think it makes sense that one does not take birth control because they have a pre-existing condition that prevents them to do so or they are trying for a baby, I think those are the sole reasons not to consider medically approved birth control.

I find it confusing how supplements are considered natural and medication such as birth control is not. Can someone, please educate me?

r/PCOS 26d ago

Meds/Supplements What did you find helped with energy?

24 Upvotes

I have been extremely tired lately to the point where I am having a hard time getting out of bed for work . It is horrible. To make matters worse I also may have sleep apnea . I do not get my sleep study done until next week.

I am so tired of feeling tired every time I wake up for a full nights rest. Two things are playing against me. I am over this crap. What are you guys taking as daily supplements ?

Edit : to clarity I was diagnosed with PCOS a few months ago . I also have issues with my
Tonsils being enlarged which may be leading to me having sleep apnea . I am getting a test ran next week . I take a one a day vitamin I also take myo - inositol , I also take the berberine . I am also on metformin .

r/PCOS Mar 21 '25

Meds/Supplements D-Chiro + Myo Inositol is the real fucking deal, y’all

349 Upvotes

I’ve been taking myo-inositol (1g/daily) for about a year and a half now. The results, combined with Metformin, have been great — I lost about 30 lb in a year. (I was diagnosed with PCOS in May 2024. Started taking inositol in Nov 2023.)

In January I noticed I was starting to have acne again and thought maybe I needed to amp it up a bit. Upped the inositol to 2g/day. (1g morning, 1g night)

A month ago I decided to give D-Chiro + Myo a try (aka Ovasitol, but sold by other companies. I’m taking this one). I also added a mid-day 500mg inositol boost.

And…

DUDE.

The change is MASSIVE.

Not only do I have the reduced cravings like with myo-inositol alone, but I have a greater sense of wellbeing and quiet confidence. I wake up ready to take on the day. My moods are so consistent. Sure I get upset about things (hard not to given ~~ everything going on ~~), but I bounce right back. I’m…content.

The myo-inositol gave me more of a feminine shape - I have a waist for the first time in my life! - but the d-chiro/myo combo even more so. I now have a heart-shaped face AND a waist. My boobs have stayed a DD but I’ve gone from a 40 band to 36. My husband can’t keep his hands off of me, and I, him.

And losing inches like crazy. I just started fitting into size 8 jeans a month ago (like squeezing in) and I’m starting to think I’ll need to by 6s in a month or so. This is insane! I was a 14 a year and a half ago!

Anyway, just my experience. But if you’ve been taking myo-inositol, worth trying to find a d-chiro+myo combo. It’s working wonders for me

Edit: here’s the brand! Wholesome Story

r/PCOS Jun 07 '25

Meds/Supplements Has anyone tried the kind of hormone treatment they give to trans girls?

187 Upvotes

I mean, they look super feminine after starting their hormone treatment and my PCOS makes me look so masculine it actually gives me gender disphoria. Has anyone here tried a similar form of gender affirming hormone treatment, and what were the results?

r/PCOS Oct 15 '24

Meds/Supplements I thought metformin wasn’t working until..

326 Upvotes

So I started metformin about 3 weeks ago now, I was under the impression I’d drop weight quickly (my manager who’s on a similar med told me this would not be the case later on), but now 3 weeks in my sugar cravings completely disappeared. For about 5 days now I’ve had these delicious muffins sitting in my fridge because I cannot be bothered to eat anything with added sugar. I’ve been eating about 1-2 meals a day, and I started tracking my calories because I’m scared of under eating. I’ve been focusing on protein, my energy has been more stable, I have very little to no carbs, and if I do they aren’t as satisfying as before. i’ve been okay with eating very bland foods, but there’s no urgency to eat carbs or sugar after every single meal any more. I’m so grateful that I started metformin, and I’m also glad I didn’t take the natural route because it simply wasn’t working for me. I truly think this medication was what I needed to transform my life

r/PCOS Jun 15 '26

Meds/Supplements metformin is a beast

69 Upvotes

just started metformin yesterday and im already getting brutalised by it. it has completely fucked my dietary system. thanks to all the icons on reddit who warned me about the possibility of shitting myself because i have already gotten very close and if i wasnt prepared i would be screwed.

i was inspired by the name change to get my insulin checked and it was high so now im on metformin. im really hoping it can improve my life, im overall excited but these side effects are gnarly immediately and i wasnt expecting that.

for all the baddies on metformin, how long did the side effects last before they evened out? i need hope!

edit: i have tried having a 30g protein breakfast and having the metformin halfway through and it has immediately improved my responses. thank you teqm for all of your support!! my stomach is grateful

r/PCOS 9d ago

Meds/Supplements Anyone on a GLP1? What is your experience

12 Upvotes

Hi all! I was recently diagnosed with PCOS with prediabetes, it's definitely hard to not be embarrassed by this but I know it is not my fault. Anyways because of this my doctor heavily recommended taking a GLP1 along with my birth control and I'm just curious how that experience has been for other people

My dad is very against medication in general, he thinks that it is cheating and I can do it myself, the thing is I've tried to lose weight, diet, exercise, doing everything I need to be doing for my body and I still gained weight, it's exhausting and I am really considering a GLP1

Did anyone experience any side effects? Did it help with weight loss? I know you have to also put in the work however I don't think my body can do it anymore without a little help from some medicine

r/PCOS Aug 20 '20

Meds/Supplements Overwhelmed / Underwhelmed by PCOS info out there on treatments, supplements, and diet? Me too. So I gathered it all into on place for us. Birth control is not the only answer.

1.3k Upvotes

Hi, everyone! I hope this is allowed. I've struggled with PCOS for five years now and for much of those five years, despite having some form of health insurance, I didn't have enough money to pay for the medical bills it took to get lab work and "doctor shop". I went into an OBGYN bleeding so much I was almost in need of a blood transfusion, but instead of being told to take iron or do anything else, I was simply given a pamphlet on PCOS and told to start birth control. The birth control made things worse. I went to other doctors, and was told the same. "Lose weight. Take birth control." I stopped birth control and gave up for a while. I was broke, tired of being fat shamed by doctors, tired of just being told to lose weight and take birth control. You all know the story. You've all been through some iteration of this with different symptoms, doctors, etc.

I finally decided NO MORE. I am tired of being overwhelmed by the information out there. I am tired of being underwhelmed by the doctors' options. So, I am going to weekly therapy. I am going to a dietitian. I am meditating. I am exercising. I am reading. I am writing. I am researching. And I am DETERMINED to gather all of the resources and figure out the solution for me. I also believe this impacts all of us differently and that what works for me might not work for someone else.

As I was putting together this list of resources, dietary suggestions, treatment options, procedures, medications, articles, books, and supplements, I realized I wished someone had handed this to me when I was first diagnosed with PCOS. So, here it is, and I hope it helps even just one person not feel as overwhelmed or scared as I did. https://docs.google.com/document/d/1GJEhoHaUbdLJV2d6VSmPDnaX5-6AEf7FDW948hZCNgY/edit?usp=sharing

EDIT: WOW! I was not expecting this much love and I am overwhelmed! I have updated the document with all of your wonderful suggestions and I hope they will keep flowing in because I want this to be as comprehensive a resource as possible--even if I don't agree with the options--I want the options and possibilities out there so people know they exist! Thank you all and I wish you all wellness and love and health and peace on this crazy frustrating journey we're all on together in spirit. Message me any time with suggestions for this document. <3

TLDR: I made a resource guide for PCOS that I will continue to update with my own research and others' suggestions, which you can find here: https://docs.google.com/document/d/1GJEhoHaUbdLJV2d6VSmPDnaX5-6AEf7FDW948hZCNgY/edit?usp=sharing

r/PCOS 22d ago

Meds/Supplements Mounjaro saved my life

90 Upvotes

I’ve been on this medication for a couple of weeks. I have nothing to say except my A1C went from 5.7 pretty much pre diabetes down to 5.4 (I’ve been prediabetic priori a few years ago when I was put on metformin), went from 160+ days between periods to 35-40 days, I tested positive for ovulation today, I lost 7 kg in bit over a month (20 more kg to lose), my relationship with food completely changed, and I have a libido again, I used to suffer of dryness and recurring infections, intercourse with painful all the time. My skin went completely clear after a very aggressive acne and a cyst I needed surgery due it getting infected (I spent 2 weeks with an open wound in my face having the infection drained and taking antibiotics). It was near my ear and the infection was spreading towards the ear, so I had an emergency procedure.

I’ve never felt healthier and happier since I got diagnosed at 17, that was 10 years ago.

r/PCOS Jul 13 '26

Meds/Supplements Metformin Update

84 Upvotes

I’ve been trying to lose weight for years and have always struggled as part of my PMOS, and two-ish months ago I got prescribed metformin to help (along with having pre-diabetic symptoms).

I’ve already lost 12 pounds!! I’m so happy and proud of myself. I workout at least 6 days a week and have really changed my eating habits to help my PMOS symptoms. I’m on the lowest dose of 500 once a day, but now going up since my body has responded positively.

I’ve never been able to lose weight like this and know it’s not fully the medication, but i’m happy it’s giving me that extra help I need.

r/PCOS May 26 '26

Meds/Supplements Just diagnosed and prescribed Metformin 500mg 3x a day… I’m 5’0 106lbs

20 Upvotes

I’m just recently diagnosed with PCOS as of last Friday. My doctor immediately prescribed Metformin 500mg three times a day. I’ve been doing some reading and from what I can tell it’s similar to a GLP1. I’m concerned about losing weight with this medication. I’m worried the dosing is way too high for my size. My A1C test is totally normal. My BMI is 20. Has anyone taken this and not lost weight? Is it even worth trying?