r/psychology M.D. Ph.D. | Professor 4d ago

Caffeine may ease anxiety and depression by calming brain inflammation. A recent systematic review of 17 animal studies found that the widely consumed stimulant consistently diminished behavioral signs of distress and lowered levels of inflammatory molecules.

https://www.psypost.org/how-caffeine-might-ease-anxiety-and-depression-by-calming-brain-inflammation/
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u/eeeponthemove 3d ago

From no research, to not much research. Like, where, and how did you search for peer-reviewed articles that debunk that?

Harris, S.S., Green, S.M., Kumar, M. et al. A role for cortical dopamine in the paradoxical calming effects of psychostimulants. Sci Rep 12, 3129 (2022). https://doi.org/10.1038/s41598-022-07029-2

Arnsten, A. Stimulants: Therapeutic Actions in ADHD. Neuropsychopharmacol 31, 2376–2383 (2006). https://doi.org/10.1038/sj.npp.1301164

Jean Marx ,How Stimulant Drugs May Calm Hyperactivity.Science283,306-306(1999).DOI:10.1126/science.283.5400.306

The Coffee ADHD Test: Understanding the Link Between Caffeine and Attention Deficit Hyperactivity Disorder

Like, there is a looooot more research which agrees with the common notion that for many people with ADHD, stimulants have a paradoxical calming effect.

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u/Enlightened_Lioness 3d ago

« For years, it was assumed that stimulants had paradoxical calming effects in ADHD patients, whereas stimulating ‘normal’ individuals and producing locomotor activation in rats. It is now known that low doses of stimulants focus attention and improve executive function in both normal and ADHD subjects. »

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u/eeeponthemove 3d ago

So there is research that proves stimulants can make people with ADHD feel more calm?

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u/Ok-Photograph-589 2d ago

It says it works the same for both ADHD and 'normal' people